The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA, maintain and differentiate hematopoietic stem cells, and use ubiquitin signaling to propagate cellular signals. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.

Our work is supported by the NIH, Li Ka Shing Foundation, Heritage Medical Research Foundation, the California Institute for Regenerative Medicine, and the Fanconi Anemia Research Fund.


February 5, 2018

Farewell to Benjamin Gowen, Hong Ma, and Rachel Valenzuela

Farewell to our great co-workers. Your hard work and dedication were an important part of our team.

Benjamin Gowen joined our lab as a Postdoctoral Fellow in...

October 11, 2017

Congratulations to Jenny, Emily, and Jacob for their latest publications!

Our Post Doc researcher Jiyung Jenny Shin together with our PI Jacob Corn have recently published the “E Pluribus Unum (“Out of Many, One”): CRISPR...

October 5, 2017

Jacob Corn awarded the prestigious NIH “New Innovator” Grant

IGI Scientific Director of Biomedicine Jacob Corn has received the NIH Director’s New Innovator Award that provides $1.5 million over five years to...

News Archive


Blog - Making the Cut

June 12, 2017 1 Comment

Shapers and Mechanists

There’s a series of cyberpunk short stories and a book written in the 1980s by Bruce Sterling called The Schismatrix. It centers around two major offshoots...

June 1, 2017 1 Comment

Backpacking season

It’s important to spend time outside the lab. And before you ask, that’s not why the blog has been dormant. I was teaching this last semester (a general biochemistry...

November 9, 2016 0 Comments

Sequence replacement to cure sickle cell disease

My lab recently published a paper, together with outstanding co-corresponding authors David Martin (CHORI) and Dana Carroll (University of Utah), in which...

September 12, 2016 1 Comment

Improved knockout with Cas9

Cas9 is usually pretty good at gene knockout. Except when it isn’t. Most people who have gotten their feet wet with gene editing have had an experience like...

Blog Archive

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to: