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The Corn Lab
The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA, maintain and differentiate hematopoietic stem cells, and dispose of entire organelles. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.
Our work is supported by the Swiss National Science Foundation, the European Research Council, the NCCR RNA & Disease, the Fanconi Anemia Research Fund, the Bill and Melinda Gates Foundation, the NOMIS Foundation, and the Lotte und Adolf Holtz Foundation.
News
January 24, 2020
Choosing the right path in genome editing – review published in Nature Cell Biology
Genome editing is all about DNA repair. So if you want to get your cells to do more of what you want (*cough* HDR *cough), you’d better know how they make ...
September 13, 2019
CDN transporter collaboration with David Raulet published in Nature
Cells have many ways to figure out that something is wrong. One of these is cGAS, which makes a cyclic dinucleotide (CDN) to activate STING innate immune signaling....
August 8, 2019
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