Overview

The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA and use ubiquitin signaling to propagate cellular signals. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.

News

March 28, 2017

#1 spot in the Media Highlights: The 10 Essential Stories of 2016

The top UC Berkeley story last year features our postdoctoral fellow Mark Dewitt using the CRISPR-Cas9 gene-editing tool to cure the sickle cell disease.  ...

March 27, 2017

Welcome, Jonathan Vu!

We’re delighted to welcome Jonathan to join our lab as a Research Associate.  He has been working as a volunteer before and will continue to work ...

March 23, 2017

Thomas Barnes from Intellia Therapeutics gave a talk to Corn Lab

The management and research teams from Intellia Therapeutics came to visit UC Berkeley today. Thomas Barnes, Ph.D., the Senior Vice President of Innovative...

News Archive

Tweets

Blog - Making the Cut

November 9, 2016 0 Comments

Sequence replacement to cure sickle cell disease

My lab recently published a paper, together with outstanding co-corresponding authors David Martin (CHORI) and Dana Carroll (University of Utah), in which...

September 12, 2016 1 Comment

Improved knockout with Cas9

Cas9 is usually pretty good at gene knockout. Except when it isn’t. Most people who have gotten their feet wet with gene editing have had an experience like...

August 29, 2016 0 Comments

Safety for CRISPR

This post is all about establishing safety for CRISPR gene editing cures for human disease. Note that I did not say this post is about gene editing off-targets....

July 5, 2016 0 Comments

CAR-Ts and first-in-human CRISPR

(This post has been sitting in my outbox for a bit thanks to some exciting developments in the lab, so excuse any “dated” references that are off...

Blog Archive

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JCORN@BERKELEY.EDU

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