The Corn Lab

The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA, maintain and differentiate hematopoietic stem cells, and dispose of entire organelles. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.

Our work is supported by the Swiss National Science Foundation, the European Research Council, the NCCR RNA & Disease, the Fanconi Anemia Research Fund, the Bill and Melinda Gates Foundation, the NOMIS Foundation, and the Lotte and Adolf Hotz-Sprenger Foundation.

News

January 30, 2025

C-TERMINAL AMIDES FUNCTION AS SIGNALS FOR PROTEIN DEGRADATION- PUBLISHED IN NATURE

Proteins are essential building blocks of life, but they can become toxic to our cells if damaged, for example under oxidative stress. In turn, human cells ...

January 20, 2025

Congratulations to Zac who was awarded an ETH grant!

We are thrilled to announce that GEML has been awarded an ETH grant to advance its pioneering research into the biological mechanisms driving phenotypic variability...

January 16, 2025

Congratulations to Charles and Lilly on the BRIDGE Discovery grant!

We’re happy to announce that Charles and Lilly received the BRIDGE Discovery supporting HT-DISCOVER, an exciting new technology for detecting genome...

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Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JACOB.CORN@BIOL.ETHZ.CH

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