The Corn Lab

The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA, maintain and differentiate hematopoietic stem cells, and dispose of entire organelles. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.

Our work is supported by the Swiss National Science Foundation, the European Research Council, the NCCR RNA & Disease, the Fanconi Anemia Research Fund, the Bill and Melinda Gates Foundation, the NOMIS Foundation, and the Lotte and Adolf Hotz-Sprenger Foundation.

News

August 22, 2024

THE GENOME GATEKEEPER: TREX1 RESTRICTS CRISPR-CAS9 GENOME EDITING, PUBLISHED IN NATURE BIOTECHNOLOGY

CRISPR-Cas9 gene editing is widely used to introduce targeted mutations in cells and organisms. During the gene editing process, Cas enzymes induces a double-strand...

August 9, 2024

Welcome Luca!

Luca received his Master’s degree in Biological Chemistry from the ETH Zürich in 2024. Luca joined the Corn Lab as a Research Assistant in July 2024; his research...

August 6, 2024

Welcome to Lily!

Xinhe (Lily) Zheng received her Bachelor’s degree in Molecular and Cell Biology from UC Berkeley in 2023. Lily joined the Corn lab in early July 2024. For her...

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Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JACOB.CORN@BIOL.ETHZ.CH

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