Overview

The Corn Lab develops and uses next-generation genome editing and regulation technologies. We work on both fundamental biological discovery and potential therapies for human genetic diseases. Our focus is the mechanisms by which cells repair their DNA and use ubiquitin signaling to propagate cellular signals. Through technology development, mechanistic cellular biochemistry, and translational projects, we are working to unravel complex cellular phenotypes to further biological understanding and improve human health.

News

May 9, 2017

Watch Out!

Watch Out!  Incredible breakthroughs in Science are breaking through this door....

May 5, 2017

Sharon Feng receives the SURF Rose Hills fellowship

Congratulations to our undergraduate researcher, Sharon Feng!  She will receive the Summer Undergraduate Research Fellowships— Rose Hills...

May 3, 2017

How-to-guide to use Cas9 RNP for high efficiency genome editing

IGI Project Scientist Mark DeWitt and Scientific Director Jacob Corn have published a paper ” Genome editing via delivery of Cas9 ribonucleoprotein...

News Archive

Tweets

Blog - Making the Cut

November 9, 2016 0 Comments

Sequence replacement to cure sickle cell disease

My lab recently published a paper, together with outstanding co-corresponding authors David Martin (CHORI) and Dana Carroll (University of Utah), in which...

September 12, 2016 1 Comment

Improved knockout with Cas9

Cas9 is usually pretty good at gene knockout. Except when it isn’t. Most people who have gotten their feet wet with gene editing have had an experience like...

August 29, 2016 0 Comments

Safety for CRISPR

This post is all about establishing safety for CRISPR gene editing cures for human disease. Note that I did not say this post is about gene editing off-targets....

July 5, 2016 0 Comments

CAR-Ts and first-in-human CRISPR

(This post has been sitting in my outbox for a bit thanks to some exciting developments in the lab, so excuse any “dated” references that are off...

Blog Archive

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JCORN@BERKELEY.EDU

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