The Corn Lab

How do good cells cope when bad things happen to them? The Corn Lab studies how human cells maintain healthy genomes, proteomes, and organelles in the face of constant stresses. We focus on fundamental biological discovery but are always on the lookout to translate these insights into potential therapies for human diseases. Our work often involves developing and using next-generation genome editing and regulation technologies, ranging from individua perturbation to functional genomics screening. Through technology development, mechanistic cellular biochemistry, and translational projects, we work to unravel complex cellular phenotypes to further biological understanding and improve human health.

Our work is supported by the NOMIS Foundation, the Lotte and Adolf Hotz-Sprenger Foundation, the Swiss National Science Foundation, the European Research Council, the NCCR RNA & Disease, and the Fanconi Cancer Foundation.

News

March 31, 2026

Welcome back to Camilla!

Camilla Micheli obtained her Bachelor’s degree in Biology from Maastricht University (UM) in 2024. She is currently enrolled in the Microbiology and Immunology...

March 26, 2026

DisTAL-Seq: A NEW METHOD TO PROFILE TALEN OFF-TARGETS — PUBLISHED IN MOLECULAR THERAPY: NUCLEIC ACIDS

Programmable nucleases have transformed genome editing, enabling precise DNA modification for both research and therapeutic applications. However, ...

March 16, 2026

SP110 PROTECTS CELLS FROM INTEREFERON-INDUCED CELL DEATH- PUBLISHED IN NATURE CELL BIOLOGY

Stimulation of the innate immune system by foreign RNA triggers a strong interferon response that helps cells defend against infection. However, this powerful...

News Archive

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JACOB.CORN@BIOL.ETHZ.CH

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