People

Principal Investigator

Jacob Corn

Principal Investigator
+41 044 633 29 80

Jacob Corn is the Professor of Genome Biology... Read Bio

Jacob Corn is the Professor of Genome Biology at ETH Zürich. His research aims to bring about the end of genetic disease through the development and application of next-generation genome editing technologies. Jacob is committed to the improvement of human health through the fundamental understanding of disease mechanisms. Over the last fifteen years he has bridged academia and industry, working in therapeutic areas that include infectious disease, neurobiology, and oncology. His graduate studies at the University of California, Berkeley redefined our understanding of DNA replication and his postdoctoral work at the University of Washington computationally designed protein inhibitors from scratch. Jacob was a group leader at Genentech where he discovered biological mechanisms for challenging therapeutic targets. Prior to joining ETHZ, Jacob was the founding Scientific Director of the Innovative Genomics Institute and faculty at UC Berkeley. In his spare time, Jacob enjoys long backpacking trips and rock climbing

You can find Jacob on Twitter and LinkedIn.

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Staff

Matteo Bordi

Research Technician
+41 44 633 40 04

Matteo received his PhD in Natural Sciences f... Read Bio

Matteo received his PhD in Natural Sciences from the European Molecular Biology Laboratory (EMBL) and the Heidelberg University in 2017, working with Dr. Anne Ephrussi, investigating the RNA-binding activity of the germline inducer Oskar protein in D. melanogaster. During his postdoc in Heidelberg he identifies the RNA-interactome of FMR1 protein in D. melanogaster by iCLIP. Matteo joined the Corn lab as research technician in September 2019.

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Kinga Csorba

Lab Manager
+41 44 633 40 04

Kinga received her Phd in Biology/Autoimmune ... Read Bio

Kinga received her Phd in Biology/Autoimmune diseases from the University of Freiburg (Germany) in 2012, working with Dr. Cassian Sitaru and Stefan Martin PhD on autoimmune skin diseases, focusing on autoantibody-mediated pathomechanisms. During her postdoc in Basel (Switzerland), she continued her research in complement-involved autoimmune pathomechanisms in SLE. Kinga joined the Corn lab as a laboratory manager and technical assistant in May 2019.

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Prisca Iseli

Administrative Coordinator
+41 44 633 45 54

Zacharias Kontarakis

Head of the Genome Engineering and Measurement Lab
+41 44 633 40 04

Zac received his PhD in Molecular Biology and... Read Bio

Zac received his PhD in Molecular Biology and Biomedicine from the Institute of Molecular Biology and Biotechnology in Crete in 2011, working with Dr. Michalis Averof on establishing genetic tools for functional developmental studies in emerging model organisms, focusing on gene trapping and site directed recombination.  He then moved to Prof. Didier Stainier Lab, initially in UCSF and later in the Max Planck Institute for Heart and Lung research in Germany, where he worked on non-coding RNAs during development and regeneration using new reverse genetics tools.  After delving into inconsistencies between different reverse genetic approaches, Zac’s interests shifted to more fundamental questions like why some mutations cause a phenotype while others don’t.  Zac joined the “Corn Lab” as Head of the Genome Engineering and Measurement Lab in August 2019.  Amongst his research interests are regulation of gene expression during physiology and disease, with a special focus on understanding penetrance and expressivity, two classical Genetics terms that are often collectively used to describe the black box that lies between genotype and phenotype.

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Markus Schröder

Bioinformatics Scientist

Markus received his PhD in Computational Infe... Read Bio

Markus received his PhD in Computational Infection Biology from University College Dublin, Ireland, working with Prof. Geraldine Butler and Prof. Des Higgins on comparative genomics in human fungal pathogens, focusing on uncovering the population structure and characterizing transcriptional networks in Candida species. Markus joined the Corn lab staff as a Bioinformatics Scientist in May 2019 from Genentech, South San Francisco, where he worked on large scale cancer genomics and familial data sets. At ETHZ, he works on CRISPR- and NGS-related computational approaches and is part of the NCCR RNA & Disease.

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Postdoctoral Fellows

Erman Karasu

Postdoctoral Researcher
+41 44 633 40 04

Erman received his Ph.D in molecular biology ... Read Bio

Erman received his Ph.D in molecular biology from Gerstner Sloan Kettering Graduate School in 2018, working with Dr. Scott Keeney focusing on the role two meiosis specific genes (cyclin B3 and Ankrd31)in mammalian meiosis. Erman joined the Corn Lab as a postdoc in May 2019, is currently using CRISPR-Cas9 mediated genome engineering to understand novel genetic pathways in response to DNA damage.

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Amos Liang

Postdoctoral Researcher
+41 44 633 40 04

Jin Rui Liang received his PhD in Cellular an... Read Bio

Jin Rui Liang received his PhD in Cellular and Molecular Physiology from the University of Liverpool, working with Prof. Sylvie Urbé and Prof. Michael Clague on the identification of deubiquitylases that regulate mitochondrial quality control and apoptosis. He joined the IGI staff as a postdoctoral researcher in March 2015, using CRISPR/Cas9 to understand the different functions of ubiquitin linkages. 

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Matthias Muhar

Postdoctoral Researcher
+41 44 633 40 04

Matthias received his PhD in Molecular Biolog... Read Bio

Matthias received his PhD in Molecular Biology from the Institute of Molecular Pathology (IMP) in Vienna in 2018, working with Prof. Johannes Zuber on the development of genetic- and transcriptomics tools for the study of gene regulation in leukemia. In July 2019 Matthias joined the Corn Lab as Postdoc to study the genetic basis of selective protein degradation. His research interests include protein homeostasis and exploratory genetics, with a special focus on protein quality control.

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Jiyung Jenny Shin

POSTDOCTORAL RESEARCHER
+41 44 633 40 04

Jenny Shin received her PhD in Metabolic Biol... Read Bio

Jenny Shin received her PhD in Metabolic Biology from University of California, Berkeley in 2016, working with Dr. Danica Chen on the regulation of mammalian aging. Jenny joined the IGI staff as a Postdoctoral Fellow in September 2016 and is currently using CRISPR-Cas9 mediated genome engineering to understand genetic pathways that control hematopoietic stem cells and metabolic disorders.

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Graduate Students

Marija Banović

Graduate Student Researcher
+41 44 633 40 04

Marija Banović received her Master’s degre... Read Bio

Marija Banović received her Master’s degree in Medical Biotechnology from University of Rijeka, Croatia, in 2015. She worked in the laboratory of Dr. Antonija Jurak Begonja, focusing on the role of phosphoinositides in proplatelets formation. Marija joined the Corn Lab as a PhD student in November 2018, using genome editing to study how cells such as hematopoietic stem cells regulate loss of their organelles. Her interests include biology of hematopoietic stem/progenitor cells and translational research with the special emphasis on the implementation of genome editing technologies for therapeutic purposes.

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Mandy Boontanrart

Graduate Student Researcher

Mandy Boontanrart received her bachelor's deg... Read Bio

Mandy Boontanrart received her bachelor's degree in Molecular Biology and Communications from the University of Wisconsin - Madison in 2011. She was as a Research Associate at Stemcentrx, Inc., where she worked on antibody humanizations and phage display for cancer stem cell markers. She joined the IGI as a graduate student in May 2016. Her research interests include immunological cell functions, protein engineering, and gene therapy for heritable diseases.

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Lilly van de Venn

Graduate Student Researcher
+41 44 633 40 04

Lilly van de Venn received her Master’s deg... Read Bio

Lilly van de Venn received her Master’s degree in Biology from ETH Zurich in 2017, working with Prof. Dr. Gerald Schwank on genome editing, focusing on the development of DNA barcodes harnessing the CRISPR/Cas9 system. Lilly joined the Corn Lab as a PhD student in December 2018, investigating DNA double-strand break repair after cleavage with different Cas enzymes and off-target detection. Her research interests include DNA repair mechanisms, as well as the potential use of genome editing for therapeutic purposes.

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Alan Wang

NSF Graduate Fellow
+1 510 664-4452

Alan received his BA in biology and anthropol... Read Bio

Alan received his BA in biology and anthropology from Amherst College in 2012, working with Professor Dominic Poccia to examine the role of diacylglycerol in shaping biological membranes. He spent a few years as a research assistant at the NIH and UCSF before coming to UC Berkeley. Alan joined the IGI as a graduate student in May 2015 and is using Cas9 to study locus specific protein composition.

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Charles Yeh

Graduate Student Researcher
+41 44 633 40 04

Charles Yeh received his Bachelor’s degree ... Read Bio

Charles Yeh received his Bachelor’s degree in Biochemistry and Molecular Biology from the University of Maryland, Baltimore County (UMBC) in 2014. He then joined the National Center for Advancing Translational Sciences at the National Institutes of Health (NCATS-NIH). As a member of the Therapeutics for Rare and Neglected Diseases (TRND) program, Charles developed and applied human stem cell-derived disease models to identify potential therapeutics for rare lysosomal storage disorders, including Farber and Wolman diseases. In 2018, he joined the IGI as a graduate student and is presently studying the mechanisms of DNA repair homology search in the context of gene editing.

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Alumni

Staff

Name
IGI Position
New Position
Ron Baik picture

Ron Baik

Research associate

Research associate at Stanford

Julia Chu

Lab manager

Lab Manager, Paredes lab at UCSF

Gemma Curie

Lab Manager

Microbiologist at Idaho State Department of Agriculture

Mark DeWitt

Postdoc and Program Manager

Katelynn Kazane

Research Associate

Hong Ma

Research Associate I

Research Associate II in Richard Kramer Lab

Jonathan Vu

Research Associate

Research Associate at the IGI

Stacia Wyman

Bioinformatics Scientist

Bioinformatics Scientist at the IGI

Elena Zelin

Research Scientist

Postdoctoral Fellows

Name
IGI Position
New Position

Benjamin Gowen

IGI-AZ Postdoctoral Fellow

Shaheen Kabir

Postdoctoral Fellow

Scientific Project Leader at UCSF

Vickie Lin

IGI-AZ Postdoctoral Research Fellow

Chris Richardson

Postdoctoral Researcher

Rachel Valenzuela

IGI-PFIZER Postdoctoral Fellow

Beeke Wienert

Postdoctoral researcher

Postdoc in Bruce Conklin's lab at the Gladstone Institutes

Graduate Students

Name
IGI Position
New Position

Emily Lingeman

NSF Graduate Fellow

Arik Shams

Graduate Student Researcher

Krzysztof Szablewski

Visiting Scholar

Undergraduates

Name
IGI Position
New Position

Saba Ahmed

Undergraduate Researcher

Paul Ayoub

Undergraduate Researcher

Leo Chen

Undergraduate Researcher

Jennifer Eunhee Chung

Undergraduate Researcher

Research Associate in Kohn Lab at UCLA

Sharon Feng

Undergraduate Researcher

working at Stanford Medicine

Elizabeth Jeon

Undergraduate Researcher

Rachel Lew

Undergraduate Researcher

Research Associate in the Haldar Lab at the Gladstone Institutes

Weihan Liu

Undergraduate Researcher

Tracie Luong

Undergraduate Researcher

Nicki Naddaf

Undergraduate Researcher

Technician in the Lareau lab.

Jordan Ray

Research Associate

Shirley Jing Shao

Undergraduate Researcher

Google Accelerated Science

Ankita Singh

Undergraduate Researcher

Undergraduate Researcher at Danica Chen lab

Elena Slobodyanyuk

Undergraduate researcher

Julia Wang

Undergraduate Researcher

Annie Yau

Undergraduate Researcher

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JACOB.CORN@BIOL.ETHZ.CH

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