People

Principal Investigator

Jacob Corn

Principal Investigator
+41 044 633 29 80

Jacob Corn is the Professor of Genome Biology... Read Bio

Jacob Corn is the Professor of Genome Biology at ETH Zürich. His research aims to bring about the end of genetic disease through the development and application of next-generation genome editing technologies. Jacob is committed to the improvement of human health through the fundamental understanding of disease mechanisms. Over the last fifteen years he has bridged academia and industry, working in therapeutic areas that include infectious disease, neurobiology, and oncology. His graduate studies at the University of California, Berkeley redefined our understanding of DNA replication and his postdoctoral work at the University of Washington computationally designed protein inhibitors from scratch. Jacob was a group leader at Genentech where he discovered biological mechanisms for challenging therapeutic targets. Prior to joining ETHZ, Jacob was the founding Scientific Director of the Innovative Genomics Institute and faculty at UC Berkeley. In his spare time, Jacob enjoys long backpacking trips and rock climbing

You can find Jacob on Twitter and LinkedIn.

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Staff

Mark DeWitt

Program Manager
+1 510 664-4452

Mark DeWitt received his PhD in Biophysics fr... Read Bio

Mark DeWitt received his PhD in Biophysics from the University of California, Berkeley. Working in the laboratory of Ahmet Yildiz, he used advanced single-molecule fluorescent techniques to gain new insight into the stepping mechanism of the cytoskeletal motor protein cytoplasmic dynein.  He joined the IGI as a Postdoctoral Fellow in September 2014. He became a Program Manager in 2016, and is currently working on clinical translation of a gene editing cure for sickle cell disease.

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Jonathan Vu

Research Associate
+1 510 664-4452

Jonathan Vu received his BS in Biochemistry a... Read Bio

Jonathan Vu received his BS in Biochemistry and Molecular Biology from UC Davis in 2015 working on plants and protein characterization. Jonathan joined the IGI as a volunteer March 2016, and became a staff research associate March 2017. He currently works with Mark DeWitt using CRISPR/Cas 9 as a potential therapeutic tool.

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Stacia Wyman

Senior Bioinformatics Scientist
+1 510 664-4452

Stacia holds a B.A. from Smith College, recei... Read Bio

Stacia holds a B.A. from Smith College, received her M.S. from the University of Wisconsin at Madison, and a Ph.D. in Computer Science from the University of Texas, Austin. Her postdoctoral work involved developing algorithms for identifying miRNAs as cancer biomarkers and analyzing whole genome sequences of tumors at the Fred Hutchinson Cancer Research Center. Stacia came to IGI in June of 2017 from Gladstone Institutes, where she worked on identifying modifiers of Parkinson’s Disease through whole genome sequencing of families. At IGI, she works on all thing computational related to CRISPR: editing outcomes, off-target effects, and CRISPR screens.

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Postdoctoral Fellows

Shaheen Kabir

IGI-AZ Postdoctoral Fellow
+1 510 664-4452

Shaheen Kabir received her PhD in the Biomedi... Read Bio

Shaheen Kabir received her PhD in the Biomedical Sciences from The Rockefeller University in New York, in June 2015. She performed her graduate research in the laboratory of Titia de Lange, focusing on understanding mechanisms of DNA repair using telomeres in mammalian cells as a model system. Shaheen joined the IGI staff as an IGI-AZ Postdoctoral Fellow in July 2015, and is using CRISPR-Cas9 mediated genome engineering and screening to study various cancers. 

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Amos Liang

Postdoctoral Researcher
+41 44 633 40 04

Jin Rui Liang received his PhD in Cellular an... Read Bio

Jin Rui Liang received his PhD in Cellular and Molecular Physiology from the University of Liverpool, working with Prof. Sylvie Urbé and Prof. Michael Clague on the identification of deubiquitylases that regulate mitochondrial quality control and apoptosis. He joined the IGI staff as a postdoctoral researcher in March 2015, using CRISPR/Cas9 to understand the different functions of ubiquitin linkages. 

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Jiyung Jenny Shin

POSTDOCTORAL RESEARCHER
+41 44 633 40 04

Jenny Shin received her PhD in Metabolic Biol... Read Bio

Jenny Shin received her PhD in Metabolic Biology from University of California, Berkeley in 2016, working with Dr. Danica Chen on the regulation of mammalian aging. Jenny joined the IGI staff as a Postdoctoral Fellow in September 2016 and is currently using CRISPR-Cas9 mediated genome engineering to understand genetic pathways that control hematopoietic stem cells and metabolic disorders.

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Graduate Students

Marija Banović

Graduate Student Researcher
+41 44 633 40 04

Marija Banović received her Master’s degre... Read Bio

Marija Banović received her Master’s degree in Medical Biotechnology from University of Rijeka, Croatia, in 2015. She worked in the laboratory of Dr. Antonija Jurak Begonja, focusing on the role of phosphoinositides in proplatelets formation. Marija joined the Corn Lab as a PhD student in November 2018, using genome editing to study how cells such as hematopoietic stem cells regulate loss of their organelles. Her interests include biology of hematopoietic stem/progenitor cells and translational research with the special emphasis on the implementation of genome editing technologies for therapeutic purposes.

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Mandy Boontanrart

Graduate Student Researcher

Mandy Boontanrart received her bachelor's deg... Read Bio

Mandy Boontanrart received her bachelor's degree in Molecular Biology and Communications from the University of Wisconsin - Madison in 2011. She was as a Research Associate at Stemcentrx, Inc., where she worked on antibody humanizations and phage display for cancer stem cell markers. She joined the IGI as a graduate student in May 2016. Her research interests include immunological cell functions, protein engineering, and gene therapy for heritable diseases.

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Emily Lingeman

NSF Graduate Fellow
+1 510 664-4452

Emily Lingeman received her Bachelor's degree... Read Bio

Emily Lingeman received her Bachelor's degree in Biochemistry from the University of Wisconsin-Madison in 2014. She worked with Dr. Tom Martin on studying priming proteins that regulate SNARE complex formation. In addition, she worked in the laboratory of Dr. Tom Record studying abortive transcription initiation by RNA polymerase. Emily joined the IGI as a graduate student in May 2015 and is using CRISPR/Cas9 to study ubiquitin regulation of membrane transporters.

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Lilly van de Venn

Graduate Student Researcher
+41 44 633 40 04

Lilly van de Venn received her Master’s deg... Read Bio

Lilly van de Venn received her Master’s degree in Biology from ETH Zurich in 2017, working with Prof. Dr. Gerald Schwank on genome editing, focusing on the development of DNA barcodes harnessing the CRISPR/Cas9 system. Lilly joined the Corn Lab as a PhD student in December 2018, investigating DNA double-strand break repair after cleavage with different Cas enzymes and off-target detection. Her research interests include DNA repair mechanisms, as well as the potential use of genome editing for therapeutic purposes.

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Alan Wang

NSF Graduate Fellow
+1 510 664-4452

Alan received his BA in biology and anthropol... Read Bio

Alan received his BA in biology and anthropology from Amherst College in 2012, working with Professor Dominic Poccia to examine the role of diacylglycerol in shaping biological membranes. He spent a few years as a research assistant at the NIH and UCSF before coming to UC Berkeley. Alan joined the IGI as a graduate student in May 2015 and is using Cas9 to study locus specific protein composition.

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Charles Yeh

Graduate Student Researcher
+41 44 633 40 04

Charles Yeh received his Bachelor’s degree ... Read Bio

Charles Yeh received his Bachelor’s degree in Biochemistry and Molecular Biology from the University of Maryland, Baltimore County (UMBC) in 2014. He then joined the National Center for Advancing Translational Sciences at the National Institutes of Health (NCATS-NIH). As a member of the Therapeutics for Rare and Neglected Diseases (TRND) program, Charles developed and applied human stem cell-derived disease models to identify potential therapeutics for rare lysosomal storage disorders, including Farber and Wolman diseases. In 2018, he joined the IGI as a graduate student and is presently studying the mechanisms of DNA repair homology search in the context of gene editing.

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Alumni

Staff

Name
IGI Position
New Position
Ron Baik picture

Ron Baik

Research associate

Research associate at Stanford

Julia Chu

Lab manager

Lab Manager, Paredes lab at UCSF

Gemma Curie

Lab Manager

Microbiologist at Idaho State Department of Agriculture

Katelynn Kazane

Research Associate

Hong Ma

Research Associate I

Research Associate II in Richard Kramer Lab

Elena Zelin

Research Scientist

Postdoctoral Fellows

Name
IGI Position
New Position

Benjamin Gowen

IGI-AZ Postdoctoral Fellow

Vickie Lin

IGI-AZ Postdoctoral Research Fellow

Chris Richardson

Postdoctoral Researcher

Rachel Valenzuela

IGI-PFIZER Postdoctoral Fellow

Beeke Wienert

Postdoctoral researcher

Postdoc in Bruce Conklin's lab at the Gladstone Institutes

Graduate Students

Name
IGI Position
New Position

Arik Shams

Graduate Student Researcher

Krzysztof Szablewski

Visiting Scholar

Undergraduates

Name
IGI Position
New Position

Saba Ahmed

Undergraduate Researcher

Paul Ayoub

Undergraduate Researcher

Leo Chen

Undergraduate Researcher

Jennifer Eunhee Chung

Undergraduate Researcher

Research Associate in Kohn Lab at UCLA

Sharon Feng

Undergraduate Researcher

working at Stanford Medicine

Elizabeth Jeon

Undergraduate Researcher

Rachel Lew

Undergraduate Researcher

Research Associate in the Haldar Lab at the Gladstone Institutes

Weihan Liu

Undergraduate Researcher

Tracie Luong

Undergraduate Researcher

Nicki Naddaf

Undergraduate Researcher

Technician in the Lareau lab.

Jordan Ray

Research Associate

Shirley Jing Shao

Undergraduate Researcher

Ankita Singh

Undergraduate Researcher

Undergraduate Researcher at Danica Chen lab

Elena Slobodyanyuk

Undergraduate researcher

Julia Wang

Undergraduate Researcher

Annie Yau

Undergraduate Researcher

Contact Us

Questions and/or comments about Corn Lab and its activities may be addressed to:

JACOB.CORN@BIOL.ETHZ.CH

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