Awards

We are thrilled to announce that GEML has been awarded an ETH grant to advance its pioneering research into the biological mechanisms driving phenotypic variability in human genetics. This project explores how cells respond to various genetic manipulations and how these adaptations influence phenotypic outcomes. By unraveling these processes, we aim to uncover key factors that shape disease traits and open new avenues for therapeutic intervention. This achievement highlights GEML’s leadership in cutting-edge genome engineering and our commitment to translating knowledge into transformative breakthroughs in human health. Stay tuned for updates on this impactful research!

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We’re happy to announce that Charles and Lilly received the BRIDGE Discovery supporting HT-DISCOVER, an exciting new technology for detecting genome editing off-targets. HT-DISCOVER is a drop-in technology that works even in established genome editing workflows, enabling safer and more effective therapies. With the support of BRIDGE Discovery, Charles and Lilly will bring this innovative technology to market in a future spin-off.

Stay tuned for more information!

For potential collaborations and partnerships involving HT-DISCOVER, please contact Jacob Corn (jacob.corn@biol.ethz.ch) and Lilly van de Venn (lilly.vandevenn@biol.ethz.ch).

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We’re thrilled to announce that Lilly has received the prestigious ETH Pioneer Fellowship! This achievement will empower her to transform her research-based technology into innovative product/service, paving the way for the launch of her spin-off, HT-DISCOVER. Her work will focus on advancing accurate and high-throughput off-target detection, ensuring precision and safety in genome engineering. 

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Mandy was awarded the Innosuisse Innovation grant to fund her translational work on developing gene therapies for hereditary blood diseases. This grant will support the expansion of her team and research.

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Mandy received the BRIDGE Proof-of-Concept grant for her research on hemoglobin diseases. The BRIDGE programme is jointly offered by the Swiss National Science Foundation (SNSF) and Innosuisse.

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One of our postdocs, Amos Liang, will be setting up his own research group at the Medical Research Council-Protein Phosphorylation and Ubiquitylation Unit (MRC-PPU) at the University of Dundee in June 2022. His group will expand on his previous work to understand the mechanisms and physiological roles of endoplasmic reticulum turnover via autophagy using CRISPR-based gene editing and genome-wide screening technology, fluorescence-activated cell sorting (FACS), mass spectrometry, fluorescence microscopy, and biochemical studies. We wish him all the best and we are excited for what the future holds for his new lab!

For more information on the research focus of Amos’ group, please visit here.

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Dani received the Helen Hay Whitney Fellowship The Helen Hay Whitney Foundation and her research goals are to develop new technologies that advance our understanding of fundamental biology, as well as increase the safety and efficacy of gene editing in human cells. She plans to approach this in two ways. First, how does chromatin state affect CRISPR-Cas activity at a single cell level? Second, can we manipulate the chromatin landscape to increase gene-editing strategies?

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Congratulations to Mandy and team for winning the audience vote at the ETH 3Pi Pitch Competition, where ETH Pioneer Fellows pitched their projects to an audience of 100 people in the startup community: https://www.startupticker.ch/en/news/eth-zurich-awards-best-pitches

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We are excited to share the news that Eric Aird and John Fielden were both awarded EMBO long-term fellowships, which support excellent postdoctoral researchers throughout Europe and the world. Congratulations both!

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Moritz was awarded a Boehringer Ingelheim Fonds (BIF) PhD Fellowship for his project to understand cell type-specific DNA repair preferences during genome editing. The Boehringer Ingelheim Fonds supports the most talented young researchers worldwide whose PhD or MD projects are aimed at experimentally elucidating basic phenomena of human life. Congratulations to Moritz!

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