Jacob Corn awarded the prestigious NIH “New Innovator” Grant

IGI Scientific Director of Biomedicine Jacob Corn has received the NIH Director’s New Innovator Award that provides $1.5 million over five years to pursue high-risk, high-reward work that could have implications for human health. The National Institutes of Health’s (NIH) High-Risk, High-Reward Research program, part of the NIH Common Fund, funded 86 awards to exceptionally creative scientists proposing to use highly innovative approaches to tackle major challenges in biomedical research.

Corn lab will use CRISPR-Cas9 gene editing to explore how cells recycle damaged organs, such as mitochondria. Dysfunction in organelle autophagy has been implicated in diverse diseases, including neurodegeneration, lysosomal storage disorders and cancer.  Corn lab will use next- generation CRISPR-Cas9 genome editing and regulation technologies, combined with cellular biochemistry and imaging to discover the pathways that signal for the remodeling and lysosomal degradation of multiple organelles.  Our work will reveal the mechanisms by which cells maintain organelle homeostasis and respond to organelle damage or stress, which could suggest new strategies to treat diseases associated with improper organelle autophagy.

SUBMIT A COMMENT

Your email address will not be published. Required fields are marked *

Filters

Latest News

March 4, 2021

Welcome to Sebastian

Sebastian joined the Corn lab as a PhD student in March 2021. He received his MSc in Biochemistry from ETH Zurich in December 2020 with his work on the therapeutic...

March 3, 2021

PnB Designer – fast help with prime and base editing

The Coronavirus lockdowns this spring disrupted many projects and students. But when life gives you lemons, make lemonade. In our lab, almost everyone took...

January 14, 2021

Congratulations to Mandy on the ETH Pioneer Fellowship

Mandy has just been awarded the Pioneer Fellowship which will allow her to transform her fundamental research into a startup focused on new treatments for ...

News Archive

Tweets