Finding the switches that control immune genes

The work of IGI scientists “Discovery of stimulation-responsive immune enhancers with CRISPR activation” was recently published in Nature. The researchers used CRISPR activation to find DNA “switches” that control key genes in the immune response and autoimmune disease. Post-doc Benjamin Gowen and PhD student Dimitre Simeonov were the lead authors. IGI Scientific Director Jacob Corn and IGI affiliate Alexander Marson jointly supervised the work. Important contributions were made by several Corn Lab members and alumni, including Mandy Boontanrart, Nicolas Bray, Therese Mitros, Jordan Ray, Gemma Curie, Nicki Naddaf, Julia Chu, and Hong Ma.  A summary of the research was featured by the UCSF News Center.

SUBMIT A COMMENT

Your email address will not be published. Required fields are marked *

Filters

Latest News

June 17, 2021

Congratulations to Eric and John on the EMBO fellowships!

We are excited to share the news that Eric Aird and John Fielden were both awarded EMBO long-term fellowships, which support excellent postdoctoral researchers...

April 11, 2021

Welcome to Xiaojing

Xiaojing received her Ph.D. from Weill Cornell Graduate School of Medical Science in 2020, working with Dr. Scott Keeney on the mechanism to regulate meiotic...

April 11, 2021

Welcome to Danielle

Danielle received her Ph.D. from Brandeis University in 2021 where she worked with Dr. James Haber to characterize the mechanisms of gene editing via single...

News Archive

Tweets