Finding the switches that control immune genes

The work of IGI scientists “Discovery of stimulation-responsive immune enhancers with CRISPR activation” was recently published in Nature. The researchers used CRISPR activation to find DNA “switches” that control key genes in the immune response and autoimmune disease. Post-doc Benjamin Gowen and PhD student Dimitre Simeonov were the lead authors. IGI Scientific Director Jacob Corn and IGI affiliate Alexander Marson jointly supervised the work. Important contributions were made by several Corn Lab members and alumni, including Mandy Boontanrart, Nicolas Bray, Therese Mitros, Jordan Ray, Gemma Curie, Nicki Naddaf, Julia Chu, and Hong Ma.  A summary of the research was featured by the UCSF News Center.

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March 15, 2022

Welcome to Martina

Martina received her BSc degree in Biochemistry at the Imperial College London, graduating in July 2020. She joined the Corn Lab in February 2022 and her Master...

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Simone received his Bachelor’s degree in Biotechnology in 2020, from the Università del Piemonte Orientale, Novara, Italy. He joined the Corn Lab in July ...

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Sam received his Bachelor’s degree in Health Science and Technology from ETH Zürich in 2021. He joined the Corn Lab as a Master student in May 2021 working on ...

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