IGI researchers increase CRISPR-Cas9 efficiency

IGI Researchers have discovered a way to increase the efficiency with which CRISPR-Cas9 technology cuts and disables genes in cells.  In culture, “knockout” cell lines allow researchers to better understand the role of genetic information, and may eventually improve therapies for human genetic diseases.  

Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes
Nature Communications | Chris Richardson, Jacob Corn, et al | August 17, 2016

Press Release
CRISPR-Cas9 breaks genes better if you disrupt DNA repair
UC Berkeley News | Robert Sanders | August 17, 2016

SUBMIT A COMMENT

Your email address will not be published.

Filters

Latest News

August 9, 2022

Congrats to Mandy on the BRIDGE grant!

Mandy received the BRIDGE Proof-of-Concept grant for her research on hemoglobin diseases. The BRIDGE programme is jointly offered by the Swiss National ...

March 15, 2022

Welcome to Martina

Martina received her BSc degree in Biochemistry at the Imperial College London, graduating in July 2020. She joined the Corn Lab in February 2022 and her Master...

March 15, 2022

Welcome to Simone

Simone received his Bachelor’s degree in Biotechnology in 2020, from the Università del Piemonte Orientale, Novara, Italy. He joined the Corn Lab in July ...

News Archive

Tweets