IGI researchers increase CRISPR-Cas9 efficiency

IGI Researchers have discovered a way to increase the efficiency with which CRISPR-Cas9 technology cuts and disables genes in cells.  In culture, “knockout” cell lines allow researchers to better understand the role of genetic information, and may eventually improve therapies for human genetic diseases.  

Non-homologous DNA increases gene disruption efficiency by altering DNA repair outcomes
Nature Communications | Chris Richardson, Jacob Corn, et al | August 17, 2016

Press Release
CRISPR-Cas9 breaks genes better if you disrupt DNA repair
UC Berkeley News | Robert Sanders | August 17, 2016

SUBMIT A COMMENT

Your email address will not be published. Required fields are marked *

Filters

Latest News

May 12, 2025

Welcome to Dora!

Dora obtained her Master’s degree in Chemistry from ETH Zurich in 2019, where she conducted research on the Synthesis of trypanothione reductase inhibitors...

April 22, 2025

Welcome back to Dominic!

Dominic Mailänder received his Master’s degree in Molecular Health Sciences from ETH Zurich in 2024. Dominic returned to the Corn Lab as a Research ...

April 10, 2025

SYNTHETIC LETHALITY IN DNA DAMAGE RESPONSE- PUBLISHED IN NATURE

The DNA damage response (DDR) protects the genome from myriad insults. Indeed, because endogenous damage is an existential and continual threat, cells achieve...

News Archive

Tweets